Antibiotics such as Cipro, Levaquin, Avelox are a group of antibiotics called Floroquinolones. They are among the most commonly prescribed antibiotics in the United States.
With this class of antibiotics there are great risks that can come from taking these so make sure that when prescribed these that your condition is a serious one and not a minor problem like a UTI or sinus problem.
When I consult with people all over this country, several of the chronically ill have been “floxed” as has been termed, damaged by the Floroquinolones. These individuals have had a neurotoxic reaction due to the ability of fluoride to penetrate the blood brain barrier and attack the brain.
I initially learned about this toxicity while researching for my book on Peripheral Neuropathy, “ Feet Don’t Fail Me Now.” Peripheral Neuropathy is just one of many problems that can occur due to this toxicity. More common symptoms are tingling, numbness, vertigo, loss of balance, memory issues, tendon ruptures, joint pain, ringing in the ears, rapid heart beat, intolerance to heat or cold, rashes.
So individuals that have been compromised by genetic susceptibilities, MTHFR, methylation, detoxification and the ability to handle chemicals and or toxins properly get a dose of these fluoride quinolones and this creates an inflammatory state in the body affecting the nervous system, musculoskeletal, gastrointestinal, and autonomic and cardiovascular system.
As we have learned with Genetics they can be turned on and off by diet and lifestyle changes. With floroquinones there can be an immediate reaction and or a cumulative effect where it actually will build up in the system and can affect you years down the road.
Is it possible that taking Cipro created the Peripheral Neuropathy or Tinnitus years down the road? Is this what idiopathic neuropathy is? Where there is no known identifiable cause but it is a chemical toxicity caused by an insult to our peripheral nervous system.
It has also been reported that this can than cause an increase in oxidative stress and consequential mitochondrial damage. This creates an incredible amount of fatigue, as the mitochondria function is to produce ATP, the energy of the cell. In my research with treating thousands of patients I have come to learn how important the mitochondria is for restoring a person back to health. In the past I would focus on adrenals and thyroid, which still play an important role, however if the mitochondria are not healthy than the body cannot protect itself from the continual onslaught of oxidative stress and the ability to produce energy, there will be no recovery.
Genetics does play a part. Besides the MTHFR gene, the CYP, NDUF, G6PD, NOS, CAT and SOD are important snps for methylation, detoxification and mitochondrial health.
There is no known cure for Floroquinolone toxicity however supporting the mitochondria, reducing oxidative stress, reducing brain inflammation, glutathione support and improve the detoxification pathways is a great place to start.
Functional Medicine focuses on finding the root cause of the problem. When discovered solutions become much clearer.